Herpes Simplex Virus Triggers and Then Disarms a Host Antiviral Response
نویسندگان
چکیده
منابع مشابه
Herpes simplex virus triggers and then disarms a host antiviral response.
Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human embryonic lung cells that prevents plaquing of a variety of viruses. Microarray analysis of 19,000 human expressed sequence tags revealed induction...
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Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such as Epstein-Barr virus (EBV, Human Herpes virus -4</...
متن کاملAntiviral activity of root extracts from Tagetes minuta against Herpes simplex virus (HSV-1)
A large number of plants have been used by various societies for the treatment of disease. Tagetes minuta L. (Asteraceae) is an annual species native of South American, although it has became widespread throughout the world. It is used in medicinal tea and condiments. Decoction of the plant is used as beverage and as a remedy for common cold, digestive system complaints, stomach upsets, diarrhe...
متن کاملAntiviral activity of root extracts from Tagetes minuta against Herpes simplex virus (HSV-1)
A large number of plants have been used by various societies for the treatment of disease. Tagetes minuta L. (Asteraceae) is an annual species native of South American, although it has became widespread throughout the world. It is used in medicinal tea and condiments. Decoction of the plant is used as beverage and as a remedy for common cold, digestive system complaints, stomach upsets, diarrhe...
متن کاملHerpes simplex virus eliminates host mitochondrial DNA.
Mitochondria have crucial roles in the life and death of mammalian cells, and help to orchestrate host antiviral defences. Here, we show that the ubiquitous human pathogen herpes simplex virus (HSV) induces rapid and complete degradation of host mitochondrial DNA during productive infection of cultured mammalian cells. The depletion of mitochondrial DNA requires the viral UL12 gene, which encod...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2001
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.75.2.750-758.2001